New Publication in the Journal of Endocrinology

Publication title: Developmental programming of the HPA axis and related behaviours: epigenetic mechanisms. This paper is part of a thematic section on 30 Years of the Developmental Endocrinology of Health and Disease. The paper highlights the mechanistic studies linking early exposures to adversity with changes in gene regulatory mechanisms.   The citation for this article can be found on the “Publications” page of the website, under the tab titled “The Lab.” Alternatively, th...
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Research Days for the Departments of Physiology and Obstetrics & Gynaecology 2019

  On Thursday May 2nd and Friday May 3rd, the Matthews Lab attended the annual research days for the Departments of Physiology and Obstetrics & Gynaecology, respectively. These research days provide an important platform for trainees to present their research to their fellow peers. This was the 39th annual Frontiers in Physiology (or "FIP") research day, which welcomed Dr. Richard D. Palmiter as the Keynote Speaker. Dr. Palmiter, from the University of Washington and the Howar...
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66th Annual Scientific Meeting of the Society for Reproductive Investigation

  Between March 12th and March 16th 2019, the Matthews Lab (Andrada, Dr. Sasaki, Dr. Imperio, and Dr. Matthews) attended the 66th Annual Meeting of the Society for Reproductive Investigation (SRI) in Paris, France. The meeting is provides a a platform for some of the leading scientists in the world to share their research in reproductive sciences and women's health. It also provides a tremendous opportunity for trainees to share their own research and learn from the leaders in their ...
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New Publication in the Journal of Neuroendocrinology

Publication title: Prenatal programming of stress responsiveness and behaviours: Progress and perspectives. Congratulations to Dr. Hamada and Professor Matthews on the publication of their manuscript. The citation for this article can be found on the "Publications" page of the website, under the tab titled "The Lab." Alternatively, the article can also be accessed here. This review highlighted the key literature pertaining to parental stress prior to conception and during pregnancy, an...
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New Publication in the Journal of Developmental Origins of Health and Disease

Publication title: Genome-wide epigenetic signatures of childhood adversity in early life: Opportunities and challenges. Congratulations to Dr. Sasaki and Professor Matthews on the publication of their manuscript. The citation for this article can be found on the "Publications" page of the website, under the tab titled "The Lab." Alternatively, the article can also be accessed here. This review highlighted the key literature pertaining to early childhood adversity and the associated ep...
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New Publication in Scientific Reports

Publication title: Antenatal Glucocorticoid Exposure Results in Sex-Specific and Transgenerational Changes in Prefrontal Cortex Gene Transcription that Relate to Behavioural Outcomes. Congratulations to Dr. Constantinof, Dr. Moisiadis, Alisa Kostaki, and Professor Matthews on the publication of their manuscript. The citation for this article can be found on the "Publications" page of the website, under the tab titled "The Lab." Alternatively, the article can also be accessed here. This...
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New Publication in the Journal of Cellular and Molecular Medicine

  Publication title: Gestational age-dependent gene expression profiling of ATP-binding cassette transporters in the healthy human placenta. Congratulations to Dr. Imperio, Mohsen Javam, Tam Lye, Dr. Constantinof, and Professor Matthews on the publication of their manuscript. The citation for this article can be found on the "Publications" page of the website, under the tab titled "The Lab." Alternatively, the article can also be accessed here. This study aimed to investigate t...
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New Publication in Endocrinology

Publication title: A Single Course of Synthetic Gluococorticoids in Pregnant Guinea Pigs Programs Behaviour and Stress Response in Two Generations of Offspring Congratulations to Dr. Moisiadis, Alexandros Mouratidis, Alisa Kostaki, and Professor Matthews on the acceptance of their manuscript. The citation for this article can be found on the "Publications" page of the website, under the tab titled "The Lab." Alternatively, the article can also be accessed here. This study aimed to inve...
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Lab Retreat

July 20, 2018 The lab got together for a fun retreat this summer, at Dr. Matthews' cottage! Everyone had a fun time beating the summer heat by taking a swim in the lake, or water skiing. This was also a great opportunity to get to know our three new Masters students, who will begin their graduate studies in the fall: Chris, Cindy, and Connor.
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Birthday Lunch + A Long Weekend

June 29, 2018 The Matthews lab went out for a group lunch at Margarita's in order to celebrate Alice's birthday. Alice is undoubtedly the glue that holds the lab together and we would all be completely lost if it weren't for her keeping everyone in line. Here's to a fantastic birthday and a great long weekend, where Canada is celebrating it's 151st birthday, as well! Not that Alice is 151, of course.
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Mats Sundin Fellowship Announcement

Pictured left to right: Ursula Nosi (PhD Candidate, University of Toronto), Mats Sundin, Professor Stephen Matthews June 4th, 2018 In the Atrium of the Hospital for Sick Children, former Toronto Maple Leafs captain (and NHL Hall of Famer) Mats Sundin announced a further donation of $333,000 to support the Sundin Fellowship Program in Developmental Health between the University of Toronto and the Karolinska Institutet in Stockholm, Sweden. Mats also announced the search for the next Sun...
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70th Annual Congress of the Japan Society of Obstetrics & Gynecology

  Between May 10th and May 13th, Dr. Matthews and Dr. Hamada attended the 70th Annual Congress of the Japan Society of Obstetrics and Gynaecology in Sendai City, Japan. This conference brings together clinicians and researchers from Japan and across the globe to discuss prominent issues within the field and share their own work. On May 11th, Dr. Matthews gave a presentation titled Prenatal Programming, Epigenetics, and Transgenerational Outcomes. More information about the conference...
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35th Annual Research Day of the Department of Obstetrics and Gynaecology

  On Friday May 11th, 2018, the Department of Obstetrics and Gynaecology at the University of Toronto celebrated their 35th annual research day. This research day provides a platform for trainees (graduate students, post-doctoral fellows, medical students, residents, and clinical fellows) to present their research. This year, Dr. Tommaso Falcone was invited as the presenter of the Henderson Lecture. Dr. Falcone is a Professor of Surgery at Cleveland Cleveland Clinic Lerner College of...
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Frontiers in Physiology Research Day 2018

  On Friday May 4th, 2018, the Department of Physiology at the University of Toronto celebrated the 38th annual Frontiers in Physiology (or "FIP") research day. This day brings together the members of all four research platforms in the department in order to share the outstanding work of our trainees. This year, FIP welcomed Dr. Mona Nemer as the Keynote Speaker. Dr. Nemer is an esteemed cardiac researcher and Canada's Chief Science Advisor. In addition to the tremendous work pres...
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New Publication in Epigenomics

Publication title: The DNA methylation landscape of enhancers in the guinea pig hippocampus Congratulations to Andrea Constantinof, Vasilis Moisiadis, and Professor Matthews on the acceptance of their manuscript. The citation for this article can be found on the "Publications" page of the website, under the tab titled "The Lab." Alternatively, the article can also be accessed here This study aimed to determine the methylation state of regions of DNA in the guinea pig hippocampus that a...
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